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Help needed comparing CTX & P1NP results
Osteoporosis & Bone Health | Last Active: 7 hours ago | Replies (12)Comment receiving replies
jozer,
your CTX and NTX tell us that you aren't losing bone; Fosamax is working just as intended. I always like a measurement of P1NP because the value of loss and gain are dependent upon each other. P1NP is seldom measured with bisphosphonate use because it generally suppresses both. It is helpful to have markers before treatment and then one or two months after initial treatment.
Do you have numbers from dexa scans.
I'm linking a couple of video you might look at.
These links will lead you to other videos.
To answer the question about what CTX is too low, I'd say that the medications change the stakes. 50 ng/dL is what you'd expect if you were on Prolia. I find it dramatic for Fosamax. Though you aren't asking, I would probably rather be on a bone building medication that would raise both the CTX and P1NP. Dexa results would give a better perspective.
Replies to "jozer, your CTX and NTX tell us that you aren't losing bone; Fosamax is working just..."
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Thank you gently! Sure wish docs would share info; got these tests and there has been no communication of what results may mean. Will check videos; I've looked at some of the (I believe) Dr. Doug ones; informative. L-spine gained 3%, L-hip 2% and no change in L femoral neck in the year of Fosamax (no right info, hip replaced 10 years ago). Have heard (doc google) that too low CTX can sometimes predict a higher risk of ONJ so maybe it's time for a new drug? Doc wants Reclast but I am still in the process of getting multiple second opinions (ortho, gyne, my IBS doc for handling stomach issues on bisphosphonates, and a rheumatologist). I have been wondering about the bone building drugs...