I have MAC and Aspergillosis. I have taken V-fend the second time I had Aspergillosis. I got fibroses of liver . Stopped that drug. Then they did Amphotericin ( horrible infusion drug) caused toxicity to my body). So now I am taking 300 mg daily of Posaconozole with no side affects. My ID dr said can’t cure me. But she will just try to keep these 2 diseases at bay. This is my situation. Hope you find it helpful. Best of luck. 🙂