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Burning and itching under skin with no rash
Neuropathy | Last Active: Oct 1, 2025 | Replies (11)Comment receiving replies
@dmmeyers62
Where do you have the burning and itching?
You will want your neurologist to do a skin punch biopsy of your thigh and calf/ankle to test you for small fiber neuropathy.
Do you have diabetes? Do you know the cause of your neuropathy? It will be important to determine the cause of neuropathy so you can treat the cause. If it is idiopathic, you may only be able to treat the symptoms.
I have idiopathic small fiber neuropathy and it started with burning and pins/needles in my feet that was worse in warmer weather and at night. I take alpha Lipoic acid, acetylene l carnitine, and magnesium supplements as well as use Salonpas lidocaine patches and capsaicin cream for nerve pain. This helps my symptoms.
Replies to "@dmmeyers62 Where do you have the burning and itching? You will want your neurologist to do..."
I have iching and burning all over my body. Seen one neurologist and had a EMG and then went to Mayo neurologist who put me on duloxtine 60 (already on gabapentin 900). Came back home now seeing a new neurologist. Off both drugs because had side effects from gabapentin and recall on duloxtine. ( was up to 2800 on gabapentin doctors back here kept upping) I am pre diabetic but my celiac is really bad . My antibodies are still off the chart and I can't even eat gluten-free process foods. Thinking of going back to Mayo they were the only ones that were able to help before. I am experiencing breakouts with my dh rash Also. Not sure if it's all related.
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@dmmeyers62
I also have itching in my palms of my hands and I believe it is also tied to my cervical spinal stenosis, radiculopathy and carpal tunnel. I had carpal tunnel release surgery on my right hand and it improved and will have the left hand done later in the year. I am having cervical spine surgery next week to address the c6-c7 herniated disc causing neuropathy symptoms radiating to my arms/hands/fingers.