I am sorry to read about your wife’s diagnosis. My husband had two GBM tumors. He was diagnosed in April of 2022. They did not remove either tumor because they said they would just grow back and they wouldn’t be able to get all of the tumors anyway. We did the TMZ and radiation. He did not have the “good” genetic markers so the TMZ didn’t help. The radiation made him much worse very quickly and we only were able to do about 9 of the 30 treatments. I don’t mean to be a downer but I just wanted to let you know what might happen. The doctors never told us much about what to expect and I was never able to find others going through the same thing to ask them about what to expect. It was all new to both of us and we had virtually no support. My best advice is to never argue anymore and just enjoy what time you have left with her. That could be a few months or a few years. Just enjoy it as much as possible. Some GBM patients are doing better with newer treatments these days that we didn’t have when he was diagnosed. My husband only lasted three months. While it was not fun watching his decline, it was my honor to take care of him in his time of need. I was with him for better or worse and I weathered the “worse” at the end and did my best to comfort him. I wish you both the best.