← Return to Started Repatha - Side Effects

Discussion

Started Repatha - Side Effects

Heart & Blood Health | Last Active: 4 days ago | Replies (256)

Comment receiving replies
@jlharsh

Hi @dcody.
Your summary is helpful, thank you. I am a Mayo MN cardiology patient. My cholesterol has never been well controlled, and I have just felt worse and worse over time. My ears perked to this discussion because Repatha did not work for me. I started feeling worse and worse as I was on it and my LDL did not drop as much as expected. Inclisiran is part of what is working for me now. Mayo Clinic has figured out more of what is unique to me. With that knowledge, I am now taking drugs again that I said “never again” to because of how I felt. Switching from a “spray and pray” approach to treating what our doctors understand is happening seems to be what is working. I appreciate reading your story.

An initial question for you…why a beta blocker?

Jump to this post


Replies to "Hi @dcody. Your summary is helpful, thank you. I am a Mayo MN cardiology patient. My..."

I’m so happy for you. It seems I get the worst of the side effects with all those drugs. Inclisiran Sounds interesting, but with injections only twice a year I would be afraid I’d get the side effects (listed side effects sound like statins and Repatha) but it would then be in my system for 6 months. I have come back from statins and Repatha making me practically disabled. But, it sounds interesting.

I was told at the Mayo Clinic that a beta blocker, specifically Carvedilol, is just as effective and works just as well (apparently, for most people as well as for me) as a calcium channel blocker, specifically Amlodipine, at lowering blood pressure. They prescribe either or, or both. My brother, who is seven years older, has used both for quite a while. Switching was a no-brainer for me. I was having swelling and skin discoloration problems in my ankles, and sometimes feet and calves, while taking Amlodipine. In addition to Losartan, so far it has been more effective than Amlodipine, keeping my blood pressure below 130/80 most of the time, with sometimes as low as 110/60 and sometimes a few brief peaks to the 135/80 area. Very importantly, unlike Amlodipine, I've noticed no side effects from Carvedilol 6.25 mg twice a day. The praluent has also significantly diminished myalgia from the days of taking statin drugs as well, so now I'm back to feeling my younger self again. Of course, only time will tell how effective this will be. Hopefully, for years. I'm walking three to five days a week and hoping to lose about ten pounds to help keep metabolic and cholesterol conditions in check. It's my belief that the more natural health and fitness solutions I can find, the better it has been than taking more medications each with it's potential side effects and drug interactions. I think it's too easy for the average doctor or cardiologist to prescribe standard therapies when patients are disinclined or unable to change eating and exercise habits which would actually provide better life quality and a longer healthspan for most people.