Is anyone on PHESGO?

@varsha08, I believe that @vtn has experience with Phesgo (pertuzumab, trastuzumab, and hyaluronidase-zzxf) and can share more.

I'm sorry to hear that the new medication is exacerbating the neuropathy. How many treatments have you had so far and how many will you be getting?

Colleen Young, thank you for your response.
My first chemo was in Feb 2020 using Taxotere + Perjeta + Herceptin. After 6 chemos which ended in June 2020, I am on targeted therapy every three weeks using Perjeta and Herceptin till date and will be continuing till I become immune to it. So to answer your question, how many, more than 70 till date and will go on. The oncologist said they will change the drugs then. In short I am supposed to be on targeted therapy all my life!

I had invasive lobular HER 2 + hormone negative breast cancer (stage2). My treatment seems different than yours. 12 wks of Taxol with Perjeta and herceptin every 3wks. Then a mastectomy, radiation and more chemo (Kadcyla) which included herceptin. Treatment began 6/21 and ended 8/22.

I believe that there are several accepted treatment modalities. Options may be different in small cancer centers than in larger centers. Our age, overall health, stage of our cancer also enter into the decision for treatment.

I did develop neuropathy in my feet. It was not debilitating and didn't get any worse. It occasionally bothers me when I'm in bed and trying to sleep.

Thank you Maggieb for responding. You are right. Mine was stage 4. MBC spread to lymph nodes and liver. That is the reason they say targeted therapy for life.

Wish you the very best and forever good health!

Hi @varsha08
Thank you so much for sharing your journey. My mom (53) has recently been diagnosed with stage 4 HER2-positive, ER/PR-negative metastatic breast cancer, with liver and lymph node involvement very similar to your story.
Your post gave me real hope and strength. We’ve recommended the same treatment combo (Perjeta + Herceptin) starting from this week and I would truly appreciate any tips or insight from your experience.
Wishing you continued strength and good health. Thank you.

@imsiva My best wishes and prayers with you and your mom. Happy Mother’s Day to her!
I think being positive all through is the key. I always play prayers on YouTube while the infusion is going on. I feel it creates positive effect on the drug that is entering the body. Lots of anti inflammatory natural remedies like moringa powder, sour sop tea, warm lemon water as first thing in the morning seemed to have helped. Cruciferous vegetables have anti cancer properties so I have them in almost every meal. These are some of the tips I would like to share.
But feel free to ask me anything. I would be happy to answer and help whichever way.
Loads of good energy!
Varsha

Appreciate that @varsha08. Thanks for the insights. If I may ask, I would like to discuss a bit more reg my mum’s situation.
Thanks in advance!

@imsiva, please note that I removed your personal contact information as per the Community Guidelines (https://connect.mayoclinic.org/blog/about-connect/tab/community-guidelines/). We recommend sharing personal contact information using the secure private message function rather than in the public forum.

However, I'd also like to point out the benefit of sharing here in the support group where you all receive support and information from @varsha08 and others and learn from each other. And other people with a similar diagnosis will join in. 🙂