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← Return to PSA rising fast after SBRT
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Not a physician, but a rise in your PSA when coming off Orgovyx is not at all unexpected. I was 68, 4+3, localized. Had 5 fractions of SBRT at 7.25 Gy with a focal boost to the lesion at 40 Gy. While your nadir is 0.01, that is an artificially low value because of the ADT. Nadir plus 2.0 is a sign of biochemical recurrence.Your PSA is going to bounce around for a while. And in fact, a PSA "bounce" is seen as a positive, not a negative sign.
Here is my PSA history, and my RO and Uro think my numbers look great.
Pre-treatment PSA 7.8
SBRT Completed 12/28/2023
Orgovyx Completed 06/05/2024
DATE PSA
3/28/2024 0.09
6/28/2024 0.19
10/17/2024 0.59
1/8/2025 0.62
3/20/2025 0.65
Keep track of your PSA every 3 - 4 months. I suspect you are right on course.
Stay Strong Brother. We Got This.
Replies to "Not a physician, but a rise in your PSA when coming off Orgovyx is not at..."
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At that time, from 6/28/2024 to 10/17/2024, was PSA doubling time not (never) a concern? I guess that even if it was, there was no doubling from 10/17/2024 to 3/20/2025, and indeed your numbers look great!