I was told by my Pulmonologist to wait at least 30 minutes between my Albuterol/Saline (Smart Vest) and Tobramycin nebulizer treatments. That this would help greatly with the side effects I was having ( excessive coughing which seemed to bring the medication back up out of the lungs, dry mouth, very sore throat, hoarseness). This has helped me and I'm almost done with my first 28/30 days of the regiment. I've tried oral antibiotics and also a picc line and nothing has been able to take care of the Pseudomonas due to my Bronchiectasis.