We have app. in 2 hours, I will let you know if anything interesting transpires regarding future treatment .

JC - there was only one core of 14 with finding of 4+3 (gleason 7), and two with 3+3 . All of the rest was clear. BUT, that 4+3 contains cribriform and IDC formations. My husband is 69 and very fit and healthy.

First pathology stated IDC, and second opinion stated "possible IDC", both agreed about cribriform. Nevertheless, that one core puts my husband in "intermediate high risk" group.

PSMA showed cancer being contained in the gland and in that one single spot in prostate.

One lymph node was inconclusive but the scan was examined again by extremely experienced radiologist who told us that it is actually negative, and it was also confirmed by surgeon. So, hopefully it is negative.

All in all, unusual case with having one single core with such aggressive features :(. If it was 4+3 without cribriform and IDC decision would be more straightforward and easier. Cribriform cells tend to escape and metastasize and IDC sometimes make micro environment which almost protects cancerous cells inside those ducts. Nobody proved it yet but some studies show that most relapses after initial radiation actually happen to patients with those features and in this paper that was posted by Dailyeffort it looks like some patients that were without IDC and Cribriform before RT end up having them after failed RT. In another study IDC patients had better success with RP than RT for metastases free survival.

All in all, IMHO RP would give the best chance for elimination of aggressive features that are present at this time. What future holds only heavens know ...