Connect
← Return to What Kind of Radiation Did You Get for Your Gynecological Cancer?
Discussion
What Kind of Radiation Did You Get for Your Gynecological Cancer?
Gynecologic Cancers | Last Active: 1 day ago | Replies (129)Comment receiving replies
@dlgbb
Thank you so much for sharing how you get POLE E mutation. You are lucky to have that mutation, I just read an article saying that there is no difference with and without adjuvent treation if has the POLE mutation, and very good prognosis. But only 10% people can have that mutation. I will ask if I can get test for that through tumor cells. Thanks again for your kindness.
Replies to "@dlgbb Thank you so much for sharing how you get POLE E mutation. You are lucky..."
Connect
@zhangh73
Hello! Yes, I have read a lot of the literature too and have seen that as well! I agree - it is a pretty rare mutation, and even then there are additional characteristics that are required to be beneficial. The higher the tumor mutation burden, apparently the better. I believe ultra high was defined as greater than 100 mutations, and mine was greater than 350 mutations. The biggest factor in going forward with radiation for me was that this is still the recommended standard of care at the moment. In the paperwork associated with the clinical trial, under potential risks, cancer recurrence was listed as number one. But I do really believe the time is coming when the standard of care will change to exclude additional treatment.