@zhangh73 @naturegirl5
Hello!
The Pole mutation was diagnosed from the tumor sample taken after my total hysterectomy. I had my surgery and radiation treatment in Calgary, Alberta, Canada. At the time of my 6 week surgical follow up, I met with a radiation oncologist who discussed the Pole mutation with me. I would like to share with you the information that was given to me. The Pole mutation is associated with very good outcomes, and I was told that the positive outcomes may even offset the high grade of my tumor and the substantial lymphovascular space invasion. Despite these characteristics that were associated with poorer outcomes, I was considered low-risk for recurrence because of the Pole mutation. I was offered the opportunity to enter into a clinical trial with no further treatment - just close follow up and treatment if there was a recurrence. After discussion with my family we decided that I would do the radiation treatment as an insurance policy, just in case. But overall, it was very reassuring to know that such positive outcomes are anticipated. I hope this can provide you with some encouragement. I wish you all the best.