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Is anyone else oligometastatic with low PSA, post surgery?

Prostate Cancer | Last Active: 4 days ago | Replies (14)
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@dpfbanks

Ah, to chime in with the variant - we had uPSA tests (if that means to the 2-3 decimal)s. Last results:
11/1/2022 0.144
5/31/2023 0.199
11/30/2023 0.198
6/14/2024 0.323
8/13/2024 0.368
11/11/2024 0.430
1/7/2025 0.370
And PET 1/30/25 turned up 3 spots on lung. Bronchoscopy 3/10 and needle biopsy 4/3 confirmed adenocarcinoma of prostate origin. Liquid biopsy cTCs < 1 with low tumor burden. Relying on waiting til PSA gets to .5 or 1.0-2.0 seems too late!

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Replies to "Ah, to chime in with the variant - we had uPSA tests (if that means to..."
northoftheborder | @northoftheborder | 4 days ago

I agree about not waiting, and I'm sorry to hear about your findings.

uPSA detects anything above 0.01 (or even lower, depending on the test). While all your results count as low PSA, they're all detectable, and the last 3 range from 37–43× the minimum level uPSA can detect.

That's why I think the extra sensitivity of the uPSA test is so important for early warning of metastatic PCa recurrence. I haven't seen evidence (yet) of recurrence of regular adenocarcinoma prostate cancer with PSA < 0.01, but things could always change with more data

I hope your next round of threatments goes well

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