Do not apologize for coming into this thread. I was on bioidentical hormone creams for 20 years. It is over a year now that I have switched to the pallet therapy and I have moved up slowly. The average dose of a pallet for women is 100 MG‘s. I started on a low-dose and have moved up. I go in two weeks and I will go to the 100 mg I am doing this for bone building. He also gives me a estradiol I believe .3 pellet. I also take a compounded form of progesterone 100 MJ. I haven’t had any side effects except I feel energetic. My libido has returned after 20 years clearer thinking etc.. My doctor does a massive amount of blood work every four months he is an integrative medicine doctor not a gynecologist. He does do appointments via zoom. His name is Dr Anthony Bazzan associated with Jefferson Hospital at the Myrna Brind center in Philadelphia. He has written books and really knows about this field. Everything depends on the individual and the blood work. I will send you his link and you can read his philosophy etc.. Hope this helps you in someway. I am 68 years old.