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@psychometric

I'm 50 and was diagnosed in January with Gleason 7 (6/12 cores, two 3+3, four 3+4, max 20%), Decipher 0.56, T1C, PSMA negative, genomic testing negative except for unrelated MITF mutation. My urologist (and all subsequent surgeons and ROs) recommended treatment, however he did say that he would probably recommend AS instead of treatment if I was 65 instead of 50.

I really wanted some form of SBRT and even traveled to MD Anderson in Houston hoping I was a good candidate for radiation with their MRI Linac machine (smaller margins than Cyberknife so a reduced likelihood of rectal issues). Unfortunately, all three ROs I saw recommended against a short course of radiation because they thought it would worsen my existing urinary issues. The ROs at MD Anderson recommended against radiation altogether so I'm having surgery next month. Sounds like you're a good candidate for SBRT and have a solid RO, but you may want to consider getting a second opinion from an RO who uses an MRI-guided version, if that's feasible.

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Replies to "I'm 50 and was diagnosed in January with Gleason 7 (6/12 cores, two 3+3, four 3+4,..."

Psychometric. Thanks so much. Good luck for your surgery. I understand the decision.

I asked my RO about the advantages MRI guided and he downplayed them (of course they own the Cyberknife).

However. Someone suggested I watch a video and Dr Roach (couldn’t post it) and he downplays the MRI advantage. Sometimes data seems to point in different directions.