I did infusions for Pseudomonas, no side real side effects from the medications. Sleep was an issue, but I did adjust. However, I only did it for 3 weeks. I settled on 6 AM, 2 PM and 10 PM (plus/minus 1 hour). The infusions took 30 minutes. I usually fell asleep before 10 PM but set my alarm to wake up. That schedule let me get about 7 hours per night. Not sure if this helps. Best of Luck to you!