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Numbers After SRT/ADT

Prostate Cancer | Last Active: 6 hours ago | Replies (52)

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@jeffmarc

If you started off with radiation, not surgery then the rule is you do not do anything until your PSA rises 2 over the minimum that it ever reaches. If surgery is done then salvage radiation is recommended when the PSA rises to .2. With salvage radiation normal time to worry is after the PSA has risen three times in a row.

If you we're a Gleason seven then Six months of ADT makes sense. I can’t understand why he says you’re over treated. If you were only a Gleason 6 then maybe he was right. You want your PSA to be undetectable and your testosterone to be extremely low, So you can stop taking ADT and see if things go back to normal once your testosterone starts rising.

I sure would want to have PSA test every three months for the first year.

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Replies to "If you started off with radiation, not surgery then the rule is you do not do..."

Chippy and Jeff, the newer ‘guidelines’ say that men with rising PSA after surgery, whose PSA IS LESS THAN 0.7 should not get ADT. This is based on a large retrospective study which found that the harm is greater than the good.
However, I disagreed with this when diagnosed by my first RO since I felt that my surgical pathology of Gleason 4+3 Unfavorable made it more aggressive.
So I got a second opinion from Sloan and they agreed that, study or no study, they were using ADT. So I am sure plenty of Uro’s are saying that overtreatment is being rendered in many cases since we all usually go running for SRT at 0.2. Best,
Phil

That’s exactly what my MO is doing in my case. ADT stopped in Jan.2025 April checked < .01. See ya in July .

I started with RP- Gl 9 4/5, grade 5, with 1 pin with 10% Crib. He said the greatest danger I have at this point is being over treated. Not over treated yet. I think his point is my provider will rush to treat if I were to bust .2 again. Actually, I would put money on a private practice wanting to ring the register with treatment. My SO at the private practice won't admit there was a positive margin. My RO mentioned it, the genitourinary research hospital specialist mentioned it too. He said come see him if I hit 2 and he will be able to find it and treat it. I think high enough to find it and treat it is the key phrase. What do I know? I am a retired controls technician. I always welcome your thoughts, Jeff.