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@tdfraze

Pole Mutation noted on my Path Report

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@tdfraze What a terrible journey you've been on. Now that you've had surgery and gained back some weight are you feeling any better.

Here is some information that may be helpful to you in interpreting your pathology report.
Grade is used in gynecological cancers to characterize the appearance of the cells (from the biopsy that are sent to pathology). Stage is used in cancer to refer to whether or not the cancer has spread to other organs or places in the body.

Here is very good website that explains Grade and Stage in Gynecological Cancers:

American Cancer Society: Endometrial Cancer, Stages and Grades

-- https://www.cancer.org/cancer/types/endometrial-cancer/detection-diagnosis-staging/staging.html

Will you be starting radiation therapy starting the week of May 6?

Hi there!
In January 2025 I was diagnosed with stage 1a grade 3 endometrioid endometrial cancer with substantial lymphovascular space invasion, but with the Pole mutation. I had surgery for the removal of uterus, ovaries, fallopian tubes, cervix, lymph nodes for testing), and finished 25 external beam radiation treatments last week. I have been told that the Pole mutation is associated with very good outcomes, so think positively! Wishing you the best.