I also have BE, MAC, and ABPA, as well secondary adrenal insufficiency from years of treating my asthma with steroids. I also live in California!

I am currently on a biologic, Fascenra, to suppress my asthma reactivity. Also Spireva and a steroid inhaler. I'm not sure these meds have been effective. What has been effective is my anti-fungal course, itraconazole 200 mg x 2 - I've been healthier this year than I have been in a very long time. I'm not sure why my pulmonologist was reluctant to endorse the antifungal, but for me it has been a complete game changer. I also nebulize levabuterol and 7% saline twice a day, and I really feel the difference if I neglect those treatments. My ID doc has not pushed me to address the MAC, I presume because my ABPA has been uncontrolled and I've been hospitalized with pneumonia/sepsis/fungus five times in the past two years.

At some point, once I've stabilized (now dealing with another bout of steroid induced adrenal insufficiency), I will tackle the MAC problem. It's my understanding that it's a slow growing bug and it's my hope that there could be new treatments online in the next year or so. I also just don't feel strong enough to deal with the side effects of the BIG 3.