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Confused Grade 1 or Grade 2?

Prostate Cancer | Last Active: 17 hours ago | Replies (15)

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@surftohealth88

I agree with Survivor regarding biopsy vs. possible actual state of the prostate pathology. Often pathology shows higher grade after prostate is removed and examined. There are cases when grade is lower upon examination, but I can recall reading that scenario maybe once or twice.

If you decide to do AS please make sure to have biopsy again in 2 years, the latest. My husband had 3+3 in just 3 cores and in 5 years developed 4+7 with aggressive components of cribriform and IDC ! If he had biopsy every 2 years perhaps 3+4 would have been discovered on time and we would definitely choose treatment at that time, no question about that. With 3+4 you have so many options for complete cure with excellent results, vs. 4+3 with cribriform and IDC.
Yes, seek all of the opinions but be very proactive and push for what you want to do, we wish we knew more about correct AS and not rely on our urologist for advice and care. On the other hand, you are already talking to doctors that are inside centers of high competence and I am sure that you and your doctor will choose a good and successful path forward.

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Replies to "I agree with Survivor regarding biopsy vs. possible actual state of the prostate pathology. Often pathology..."

Penn said if I chose AS, then biopsy again in 6 months, then one year after that and then every two years after that if everything remained same. PSA every 3 months. DRE every year. I am still scared with that approach. The chances of me getting some sort of treatment is quite high within 2 to 5 years. Why not just get it done with now? Too many things going on in my mind. Waiting to see what Sloan will say. This group has been so much of help!

Surf, AS is watching the PSA multiple times a year, not every 5. At worst it's generally 6 months, and that's after 2 years of every 3 generally. Also, 4+7 isn't a legitimate Gleason, did you perhaps type that wrong? Not only is 11 not a valid number but usually the two numbers are one digit apart rather than four.