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Can anyone share their experience with Pluvicto?

Prostate Cancer | Last Active: 6 days ago | Replies (146)
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@soflada

Older gent here who has progressed through chemo, standard radiation, a variety of scans (MRI, PET, etc) and I just have my first Pluvicto injection at the beginning of May '25. Looking for folks who might be able to shed light on how the Pluvicto injections have worked/not worked and what side effects you've had to work through. I'm on multiple opioids and a steroid to control pain—as long as I maintain the regimen, things seem reasonable. Lose track of where I am in the day and things go sideways rapidly.

Thanks

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Replies to "Older gent here who has progressed through chemo, standard radiation, a variety of scans (MRI, PET,..."
jeff Marchi | @jeffmarc | May 2 11:18am

You have to realize that Pluvicto is real successful for about 1/3 of people works OK for about 1/3 and it doesn’t work at all for 1/3 of people.

There are genetic issues, however. You want to make sure to get a hereditary genetic test as well as somatic genetic test to see if you have any of these genetic anomalies.

Pluvicto genetic issues
RB1, PTen, TP53 are Pluvicto resistant
ATM & BRCA work better with Pluvicto

Did you got a hereditary, genetic test. You can get the test free at the below site as long as you live in the United States. Don’t Pick the option for your doctor to be involved. They won’t send you the kit until they speak to your doctor. A geneticist will call you to discuss the results in abouft three weeks.

Prostatecancerpromise.org

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