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Confused Grade 1 or Grade 2?

Prostate Cancer | Last Active: 15 hours ago | Replies (15)

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@pv001

My follow-up appointment at Penn was today. They would not recommend PSMA stating the low grade present. I'll check with Sloan Kettering. Penn however will do some sort of Decipher testing (which they are doing research on right now) and will call me back with details. But as @jeffmarc said, Penn is recommending treatment because a lot of cores were positive and one of their interpretation was 3+4. They said there is a good chance I will need treatment in 2 to 5 years if I go on AS. I am meeting with a Radiation Oncologist as well as a Uro-Surgeon at Sloan Kettering. I'll see if I can have John Hopkins read the slides as I hear they have some world renowned experts. But even if John Hopkins comes back saying everything is 3+3, I am still leaning towards surgery. I was told since my prostate is still normal size, they can pull the bladder up during surgery which will greatly improve incontinence. They will also do nerve sparing surgery. I don't know! This came out of nowhere. Absolutely zero symptoms even now!

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Replies to "My follow-up appointment at Penn was today. They would not recommend PSMA stating the low grade..."

Nerve sparing is no guarantee of success, unfortunately. As @jeffmarc pointed out, you have a very small amount of G3+4 so a less invasive treatment may be preferable.
Since you mention Sloan, the NYC campus performs MRI guided HIFU treatment. My friend is currently scheduled to have this done. I forgot the Dr’s name but he is Arabic. You can probably find him on their website. Best,
Phil

I understand about them not recommending PSMA stating the low grade present. That makes sense if you’re planning for radiation. But, if I was choosing surgery - and there’s rarely a medically necessary reason to do surgery - I would push hard for a PSMA PET scan,