Genetic studies

Hello @gregoria, I can understand wanting to find the cause of the neuropathic pain in your legs and hands. I only have the numbness in my legs with no pain and have also don't know the cause just that I have idiopathic small fiber peripheral neuropathy. I did do some genetic testing but I didn't have the one that looks at all of the gene variants that can affect the different medications used to treat conditions. There are some related discussions that you might find helpful if you are trying to make a decision on the testing.

-- Can Mayo help figure out what type of Neuropathy?
https://connect.mayoclinic.org/discussion/can-mayo-help-figure-out-what-type-of-neuropathy/
-- Gene Variants can affect meds, pain, supplements, neuro, etc
https://connect.mayoclinic.org/discussion/gene-variants-can-affect-meds-pain-supplements-neuro-etc/
-- Small Fiber Neuropathy and genetic testing?
https://connect.mayoclinic.org/discussion/sfn-and-genetic-testing/

I have had genetic testing for my non-diabetic peripheral neuropathy. It didn’t reveal much at all.

gregoria, it's worth the effort; will insurance bear the cost.
https://pathology.jhu.edu/autoimmune/development#:~:text=For%20most%20autoimmune%20diseases%20where,OR%20around%204)%2C%20etc.
Even if it doesn't explicate the cause of the peripheral neuropathy, it can give you insight on other aspects of your well being.
I don't mind the physician-guessing. but always prefer the science. Plus your testing will contribute to a data base which will help other people in the struggle.

Hello Gregoria,
From what I have recently read, genetic testing will look into the possibility of heredity and might explain what you're experiencing. No, I have not gone through it but I feel you should research it more before you make a decision. I'm sure there are scientifically oriented medical resources out there on the subject.
Best of luck and take care,
gus