I think it depends on individual. I went to Mayo for a diagnosis and treatment plan after CT showed bronchiectasis and probable MAC. They had me use albuterol neb, aerobika, postural drainage, huff coughing 2x day and exercise. When MAC cultures were negative and I was bring nothing up despite time spent, Mayo doc said daily was ok. I had to stop postural drainage due to reflux. I finally got into Penn’s bronchiectasis program and doc agrees daily is ok because I don’t bring up mucus. He added hypertonic 7% saline last fall to try to prevent my winter exacerbations. (I’d tried it on my own once before because of these forums to try to get mucus up. )
If I produced mucus, I’d increase the routine to 2x.
Good luck.