I have been told D must be taken with calcium in order to help bones. Never knew how important that was until osteo diagnosis. Just saw endo; he is pleased with my basically unchanged D levels (48 ish) and to keep on the 50,000 once a week. I think I will look at Vitamin K supplementation, magnesium, collagen as there seems to be positive results from a lot of you on this site. He does want to do Reclast (was on Fosamax 1 year) but I'm kicking that can down the road until I see a couple of other doctors (gyne to see what she thinks of estrogen supplementation as endo suggested seeing her, and my ortho surgeon (hip replaced 10 years ago, he happens to be an expert on bones in the tristate area but as a surgeon and bone oncologist); since there is no osteoporosis specific specialty I may as well talk to all the medical professionals!