If you can manage the pain with Tylenol and Aleve, I say stick with those. It's very difficult to get off Duloxetine. I do still have arthritis flare ups, despite also taking Tylenol (8 hr arthritis) and Celebrex (another prescription) but it's hard to tell what is flaring: arthritis? fibromyalgia? lupus? I deal with a lot of pain 24/7/365. The dizziness is the worst side effect for me but my other meds could be contributing. The dry mouth is annoying as hell. I drink lots of water.

My Rheumie started me at 60 mg Duloxetine and hasn't changed my dose. A year ago, I attended a month-long program on dealing with chronic pain. They taught me breathing and exercises which have really helped. Other than that, I do things that keep my mind off the pain! Sending you a big hug.