← Return to Please help me navigate the BMT process!
DiscussionPlease help me navigate the BMT process!
Bone Marrow Transplant (BMT) & CAR-T Cell Therapy | Last Active: May 6, 2025 | Replies (24)Comment receiving replies
Replies to "Thanks everyone @loribmt Yes, He is inpatient for atleast a month for the Transplant and after..."
Hi @anitasharma, I wanted to check in with you today to see how your husband is doing. If my calculations are accurate he is now at Day +6 post transplant? He may be starting to feel some of the side effects of the preconditioning chemo.
I wrote to you a few days ago, but knowing what a busy time this is, you may have not seen that reply. Here’s a link for you. It helps explain a few of the issues your husband may be seeing the next couple of weeks. https://connect.mayoclinic.org/comment/1293307/
Thinking of you and your husband and hoping all is going smoothly. Sending a hug and positive energy your way. ☺️
Connect

Good morning, @anitasharma. Today is Day + 1 in the world of BMT. The actual transplantation of stem cells is pretty anticlimactic, isn’t it? All the anticipation, worry, logistics of making it a possibility come down to a mere 20 minutes or so of time as the cells are infused.
Now, it’s recovery time. The next 2 weeks are usually the worst, if I can be honest. The side effects from the TBI, preconditioning chemo, meds and the newly implanted cells themselves, can be traumatic to the body.
Your husband’s BMT team will be vigilant in helping to keep him comfortable and well monitored for infection or reactions. The worst culprits are fatigue and nausea. But there may be some other side effects such as digestive tract issues, mouth sores, hair loss, etc., as the blood numbers continue to drop. However, many of those reverse quickly when the neutrophil count starts climbing after engraftment. (Approx 10-17 days or more after transplant)
Right now, those newly infused cells are tumbling along through your husband’s circulating blood looking for this special pore where they can enter the bone marrow. It’s really quite fascinating! Once engrafted, the new stem cells set up housekeeping inside the marrow and begin churning out new, healthy blood cells. If all goes as planned, the new immune system will again have the ability to recognize the cancerous cells which managed to bi-pass his old immune system. The goal being a durable remission. ☺️
How is he feeling today? Did the swelling near his ears go away?