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What's your experience with Orgovyx (relugolix)?

Prostate Cancer | Last Active: May 9 8:23am | Replies (261)

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Kind of different procedure than what I am going through. Had prostatectomy in 2014 after mri, biopsy, etc. Had rt 6 months later. PSA results after rt is < .06. Then another rt 4 yrs later due to rising PSA. In 2020 PSA was rising again, and still opted for “watching, but when PSA reached 5.5 in Oct 2024, I had a PET scan and the prostate cancer metastasized in different areas, and rt is not preferred for treatment, so I decided to have hormone therapy, Orgovyx. After 1 1/2 months of taking Orgovyx, PSA was down to .18, and In Feb 2025, my PSA was .1 but I plan to take it for a year. (My Hematologist told me to take it indefinitely.) I’m just wondering why you take Orgovyx before RT. I will be seeing my Hematologist in July and will request for PET scan if the cancer is still in my system, and will also ask to have Zytiga if it helps to kill the (remaining, if any) cancer cells. Hang in there, buddy. We will have this pass, too.

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Replies to "Kind of different procedure than what I am going through. Had prostatectomy in 2014 after mri,..."

I’m just wondering why you take Orgovyx before RT.

My guess is to weaken the cancer cells in the hopes of making the RT more effective.

Hi, my first question is did you have your prostate removed before it had spread? The reason for doing the Orgovyx before radiation is that it lowers the testosterone that the cancer feeds off of. Also helps kill or weaken the cancer so the radiation will be more effective. I will have 8 more treatments after today. Then continue the Orgovyx for a couple more months. But I was curious about things coming back for you if you had your prostate removed. I look forward to hearing back from you.