About 20 years ago my wife had a problem with C-Diff after taking clindamycin that a dentist had prescribed. It got so bad that she was headed for colon surgery if things didn't improve. No antibiotics worked. I did some research and discovered a probiotic called Culturelle(R) I was able to find it in only one pharmacy in downtown Portland, a city where I worked at the time. This turned her around and, in my opinion, saved her life. We have been taking Culturelle ever since, especially when we travel and after dining out. Once in a great while, when Culturelle doesn't quite fix an intestinal "problem," we use Florastor(R), a probiotic known for its ability to combat C-Diff.