I've read that peripheral neuropathy is not uncommon after colonoscopy, but never heard of anyone experiencing it. I've had too many of them. Usually there is a nurse who stays with you. When they introduce themselves tell them that you have a terrible time keeping your feet warm and ask if they will give you warm blankets for your feet. It you have anesthesia, you won't notice your feet during the procedure which is only about 30 minutes. Probably the only effect will be from the anesthesia. It can cause a little nausea and a day of being tired. If they remove any polyps, you could have a little blood. They stretch the colon with carbon dioxide. That can be a little uncomfortable until it escapes. I hope it's easy for you.