I had my first Reclast infusion on Friday, 4/25/25. I was very anxious about having this infusion because of some of the comments made by others who have had negative experiences with this. I expected the worst (that way, if it was not bad, I would be very pleased). I have to report that I had no side effects from Reclast. Today is Sunday, two days after the infusion. I am tired, but that may be because I have not been active after the infusion. The infusion nurse told me to rest for two days post infusion. I had the full dose and it was infused over a 45 minute period. The infusion center was very comfortable, and they were very accommodating. I was warned ahead of time to make sure and hydrate, so I started drinking a lot more water one week prior to the infusion. I was advised to take Tylenol 30 minutes before my appointment, and I did so (1000mg). I also took 2.5mg Valium at the same time, because of my anxiety about this. I am still hydrating because I think it's better for the kidneys. I think that because we are all different, some may have reactions to this and some may not, and it may depend on various factors like pre-existing health conditions, medications you currently take, etc. I don't know, but just something to consider. You can ask me anything you like about this, and I'll be happy to answer. Reclast was my only option, after having taken Fosamax, which I could not tolerate, Evista, which did nothing. Atelvia, which was fine, but I developed Barrett's esophagus, Forteo for 12 months, Prolia for 3.5 years, and Tymlos for 10.5 months. I'm glad I don't have to think about taking any drugs for this, now, for another 12 months! Thank you for listening 🙂