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PSA numbers after radiation with no ADT

Prostate Cancer | Last Active: Apr 28 6:12am | Replies (25)

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@jb2buckwater

67 Years old, had 5 treatment proton beam radiation at Mayo Rochester. PSA pretreatment 10.5.
Two years later it had dropped to 0.5. It does eems to take 2 years or longer to reach a new nadir after which we need to respond to an increase of 1 before hitting the fire alarm.

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Replies to "67 Years old, had 5 treatment proton beam radiation at Mayo Rochester. PSA pretreatment 10.5. Two..."

My SBRT has been a roller coaster. 3 opinions on biopsy. 2 said 3+4 W/cribiform. 1 said 4+3. W cribriform

Pre-treatment PSA was 9

Post-treatment:
2 months, 11.96
3 months 9.25
7 months 4.83
10 months 6.38
12 months 6.02
14 months 5.41
17 months 3.9

Test again in June.
I was the guy who had the post-radiation inflammation spike.
Then the radiation “bounce”
All doctors involved think its going well though.
PSA kinetics without ADT are unpredictable. But the thing I keep being told is that as long as it is dropping it is working.
The reason for no ADT was that I had limited positive cores 4/15. All in one area. And MRI showed a smaller than usual lesion. 3x3x7.
I'm treated at a major cancer center and my Dr said he expects it to nadir at about 1 in 2-3 years. Hopefully get to the .5 level but I have BPH and a history of prostatitis.