Test results after 6 weeks of Eligard

Posted by stew80 @stew80, Apr 16 8:59pm

Just got some blood test results after being on Eligard for 6 weeks. Do the numbers sound good for this stage?
Testosterone = 5.7 ng/dL
PSA - 0.6
I thought PSA should be even lower but maybe 6 weeks is still early.
I 'think' it's encouraging. Next step is more ADT and radiation this summer.
Gleason is 9. Cribriform and PI.

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Where did your PSA start? 0.6 sounds pretty good to me for just 6 weeks into ADT, for what it's worth. My PSA took 3 months to get from the high 60s to undetectable (< 0.01) taking Firmagon and Erleada, and the doctors thought that was pretty quick (I hadn't had radiation to the prostate yet, either).

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Stew - these are great results. You started at 12 with PSA, right? And now 0.6? Man, you really hit it good - very promising!
Phil

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Thanks Phil. You're right. PSA was 12. They did a thyroid test too. Apparently ADT can mess with it. I had no idea. I tested fine for that so far.

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@stew80

Thanks Phil. You're right. PSA was 12. They did a thyroid test too. Apparently ADT can mess with it. I had no idea. I tested fine for that so far.

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Then if your PSA has gone from 12 to 0.6 in just 6 weeks (before radiation or prostatectomy) your cancer is responding very well to ADT, and that improves your long-term prognosis — all of this coming from a layperson, of course.

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What were your numbers prior to starting for context?

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PSA 12. Gleason 9. Cribriform and PI.

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@stew80

PSA 12. Gleason 9. Cribriform and PI.

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That is great that you have such result with single drug ! Do you know what they plan as next step ?

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It looks like up to 2 years of ADT will be required. Maybe an additional drug called Abiraterone. Probably 6 weeks of Monday-Friday EBRT radiation hits. The Oncologist said they are looking to a cure, not a managed case. I think PC will always be a 'managed' scenario. Generally I think I'll end up being stable (but always monitoring of course) for the years I have left. It's just those dang treatment side-effects.

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@stew80

It looks like up to 2 years of ADT will be required. Maybe an additional drug called Abiraterone. Probably 6 weeks of Monday-Friday EBRT radiation hits. The Oncologist said they are looking to a cure, not a managed case. I think PC will always be a 'managed' scenario. Generally I think I'll end up being stable (but always monitoring of course) for the years I have left. It's just those dang treatment side-effects.

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How much Cribriform did your biopsy contain. I couldn't find my information in the portal as they have changed the portal company a few times over 3 years. Doctor would never give me the numbers after original diagnosis even while my psa started rising. I recently was doing Lupron and switched to Orgovyx for the second 3 months of my 6 months of ADT. I was Gleason 9, Grade 5, t2 stage 3 at diagnosis. Finally got in to see a genitourinary prostate cancer specialist this past week. He told me my story through all of my testing data, and I was blown away. Unknown to me I only had 1 biopsy pin with 10% Cribriform cancer. Stated he doesn't find me interesting. I laughed and said that sounds like a good thing and they all agreed and laughed. I was sentenced to 6 months ADT and 25 sessions of radiation for a missed surgical margin. He stated I now have a risk of being over treated and shouldn't seek anymore treatment unless my PSA rises to 2 (not .2). And then go see him. Gave me a 70 percent chance of never having to deal with this again. Obviously, I am thrilled but expectations are in check. I am so thoroughly disenchanted with my current SO for stringing me out due to his lack of communication. At this point he will be relegated to psa tester only. A night and day difference between a private General urology practice and a Center of Excellence, Comprehensive Cancer Center with a Genitourinary Prostate cancer specialist. Hope ran Eeyore out of the building. Best wishes on your journey.

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My biopsy report just said cribriform is 'present' (no detail re cores). I like your sentence of only 6 months ADT. I want that in my case, but I'm not doing surgery, just radiation and ADT. Otherwise, we are close in our diagnoses in terms of staging. My Oncologist finally confirmed what I had already self-diagnosed through research. High-risk localized.
Best to you as well. May you never see the bad 30%.

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