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The paradox of testosterone and ADT
Prostate Cancer | Last Active: Apr 26, 2025 | Replies (92)Comment receiving replies
Can you ever really know? Can a few rare cases turn enough heads so that doctors will respond differently to the 99.7%?
I don’t know enough about the reason for the inclusion of the carboplatin to speculate but they are certainly hitting those lung nodules hard.
We see many cases where lesions almost disappear with just ADT prior to definitive treatment but here they are going all in and not waiting for anything.
Phil
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The ‘Art’ of the science? I am not sure I could give an exact why, to be honest, other than the suspicion of a ‘sneaky’ cancer presenting very oddly. The ‘plan’ is coming from a CCOE and was modified by our local MO from what we are calling ‘quad’ therapy (triple therapy + the carboplatin) to double chemo, following by double ADT (+ ARPI) at the end of chemo. I guess we have to trust the unconventional for the win. Living with uncertainty may not be a fool’s errand.