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@lulu318

Hi, Please forgive me for my English mistakes, It's not my common language...
I know it's an old post, but like to share my experience and have yours. I'm 61 years old, I'm on Letrozole since May 2024 after having Lumpectomy and 15 strong Radiations. Everything went fine with no side affects until December, then I noticed that when I wake up in the morning, I can hardly make a fist with my right hand... than in February, I worked a lot with my hands for 2 weeks, carry a lot of heavy stuff and so... after a few days, I started to have severe pain in my inner side of left wrist and thumb base. A few days later same pains began in the right hand... the Finkelstein's test was positive and very painful for both sides.
At late March, I had some kind of Trauma to my knees, having pains that needed to use crutches for 3 weeks while taking Anti Inflammatory drugs such Etopan, Brexin and Cataflam which was the only drug that helped...
While I took the drugs for my knees, it affected my hands also, and I had a good month with almost no pain in my arms, but as soon as I finished the AI the pain in my arms return and more severe than before...
Because a month of AI drugs didn't "kill" the Inflammation in my hands, I think maybe my bilateral De Quervain's Tenosynovitis related to Letrozole... Is it possible that side affect started only 6 month after starting taking it?

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Replies to "Hi, Please forgive me for my English mistakes, It's not my common language... I know it's..."

I think these Medications are the ones doing the demage. I am on Exemestane and I was previous on Letrozole. I am only 44 years old. I have work out with weights etc for 15 years, I am an active person and eat fairly healthy. Exercising helps with my joint pain, however these meds are so bad that I even have joint pain and started having issues on my hands. So I started doing stretch and they do help. Everyday I do stretch on my hands part or my routine. The medication is the problem and no is not because the body is not producing estrogen blah blah... If that was the case then every single old women would have the same exact issues when they get old and stop producing estrogen and that's not the case. They need to come with something that doesn't destroy the body, because you are only preventing re occurrence on that breast nothing else, mean while you are destroying the rest of your body.