Im not sure. All I know is I had neuroendocrine cancer spread to my liver as well and doctor didn't give me much hope, actually no hope. So while I was taking the chemo and immunotherapy I tried the Tippens protocol and my scans were what my doctor call miraculous, she called me ecstatic she was so happy. I had ask her about the Tippens and she told me nit to take it ut could harm my liver, like chemo didnt, but when you're given 16 weeks, you basically will try anything. My tumors shrunk, some went away completely. Last year I started back with the hot flashes, then the rash and started back gaining weight all just like before so I started the protocol again. The spots were small so no chemo, all symptoms went away and spots shrunk. I stopped the protocol all symptoms are back again. So.. it may be all coincidental but I've started back taking it. I talked to a pharmacist about it and made sure none of my meds had reactions to it and she told me what ut does ut stop the tumors from being able to firm their own blood supplies this starving them basically. So please don't take my word for it as I cant swear it is what helped me, but please do your own research. I just wasn't given much anything else. The strong immunotherapy gave me ulcerative colitus that ended me up in hospital for weeks, then the steroids to help that gave me all kinds of problems which again in hospital for more weeks so the protocol i figured couldnt do worse..lol I went to Moffitt cancer center in Tampa and am seeing a thoracic oncologist, then a GI oncologist for my pancreas, another one for my kidneys heck there's so many different ones I forget who they all are. I just go fir my CTs and they pass them around..lol no one thought I'd be here because it was a high grade and spread pretty fast but something stopped it. I pray for you the best..remember your mental attitude can do wonders and I told her to start with Im not dying right now, Im not ready..she offered to call my kids maybe they could help me accept my fate..now she just says I was right..lol