I have had swollen feet/ankles almost from the start of my taking prednisone. It’s been very uncomfortable and walking is difficult. I’ve been worked up for any other causes, such as cardiac or kidney issues, and none were found. Therefore, I try to avoid sodium and increase potassium, wear compression hose, elevate my legs for an hour in the middle of the day. And I take furosemide, a diuretic. I am now at 3.5 mg of prednisone, and the swelling is still present. It has been the most annoying of all the side effects. My total weight gain has been about ten lbs. I think you just have to be patient, as the side effects can linger for a good while even after you are no longer on prednisone.