@lisalucier
The short answer to the question is yes both nausea and stomachace with the 2.4 dosage.

I started per my Mayo PCP with lowest dose of Wegovy I think was .25 but those levels did not reduct my appetite. From .25 to before starting 2.4 I had very limited stomach upset. It was more bowel movement slow down that I noticed. I did not feel nausea. I did get a slight reduction at dinner in eating feeling a little full but only at that meal.

My wife got sick and I did not start the 2.4 level dose right away. When I did within 2 hours (was prior to bedtime) I could feel nausea and stomach discomfort.

When I woke up the next morning was quite frankly severe. I was really nauseated and had stomach pain. I vomited. I struggled and sent a message to my PCP about my symptoms. At lunch time I vomited again. I was given an acute visit to Mayo.

The doctor who saw me said no way to counter the drug it has to take is time to go through system and would take about 4-5 weeks to completely leave. I was told to eat very light and clear food. My doctor said I would normally prescribed a nausea pill for you but it would interfere with other medication you take.

Now what did I do to manage it. I tried eating mashed potatoes and let them dissolve in my mouth. This light and easy digetible food did not upset my stomach and I was able to keep it down. I chew a long time and ate very slow. I need to have protein but was not going to eat any meat. So I bought protein shakes. They were tasty and did not have an issue with them.

I drank gingerale. It seemed to quell stomach. I constantly felt nausea and was burping. I stayed with the mashed potatoes and protein drinks and did not vomit again. I watch not to lay down to soon after eating as would seem cause more nausea.

I don't want to put a negative on these medications. For some they have great success with them and minor side affects. For me none of the lower doses were working to reduce appetite and the highest one I got a severe reaction.

I wish it would have worked for me but I and others need to know once you stop them your appetite and stomach will eventually return to the way it was before. So you have to try to change you lifestyle and eating habits and not just count on being on a medication like Wegovy.

My PCP wanted me to consider Expound (spell?). He said it contained 2 recptors to lower appetite not just the one in Wegovy. But I have read on MCC others having issues with Expound as well. I was told we he would not even consider it for at least three months after I had the reaction to Wegovy.

@lisalucier
Hi Lisa, I have never used Wegovy, but most likely referred to it when writing about gastroparesis. I remember stating that while gastroparesis has little recognition, I'll bet it will be getting a lot more recognition in the near future, becaue it is one of the side effects from using Wegovy and the other shots meant for diabetics, that everyone seemed to start using to lose weight. Gastroparesis hits each individual differently overall, but for the most part, hits most with feeling full before eating, and causes nausea and and in my case, when I get an attack, it starts with pain in my upper abdomen that feels like someone is cutting into it just under my ribcage. Then the nausea starts, and I have to recognize the pain across my abdomen quickly and take a Phenergan suppository, because if I don't and the vomiting and diarrhea starts, it's a 12-hour bout on the bathroom floor that ends in ungodly dry heaves that don't stop until I call an ambulance for treatment at the hospital. The last time I had to go in by ambulance they had to use two injections into the IV to keep them under control, and I'm only 10 minutes from the hospital. Then in the ER I had to receive two other kinds of IV drugs to get it to stop.
The key is to eat several meals in small amounts to not trigger the stomach spasms. Dependent upon how bad the gastroparesis is sometimes only protein shakes and bone broth are what's on my agenda, until my system quiets back down. But don't try to eat a larger meal, as the stomach can no longer digest the food in 30 minutes and it can sit in the stomach and upper bowel for 2-3 days causing toxins. Adding any food to that issue causes worsening of the gastroparesis.
I hope you are having far less problems with the Wegovy then gastroparesis, because it doesn't go away. You only learn foods that trigger it and stay away from them and not to get full. Fiber is no longer your friend because the body doesn't digest it well at all. I can get away with French style green beans and very small amounts of 3-bean salad for fiber, but that is it. Popcorn is a disaster, and so is lettuce and gaseous foods.
I hope the issue caused by Wegovy is short-lived for you, but, unfortunately if it is gastroparesis it's permanent.