I am all over the place. The NP is willing to try anything that I suggest so in the last few months she gave me Rx for Lactulose, which tastes like honey and made me ill. And now Motecrity, which I will try soon. This is after Linzess and Amitizia, both of which were awful. Linzess worked ok but I ached all over and have RA, which isn't good for me. I just have little urge to go, ever. The best improvement comes with Colace + and senna or Triphala. I have stopped worrying too. It got so bad I was dreaming about doctors telling me I had to Poo and get it out of me! If I go, fine. If not fine. The relaxed attitude has a lot to do with it. I keep track of the poo times and they average about twice a week.