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SBRT on T8 Only vs Lower Dose Pluvicto and ADT

Prostate Cancer | Last Active: 14 hours ago | Replies (5)

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@jeffmarc

Here’s the problem you may have with Nubeqa. I take it without anything else because I was on ADT for eight years and at 77 My testosterone is almost definitely not going to come back. My oncologist who specializes in prostate cancer (GU oncologist) Told me that Nubeqa Can work around at least 200-250 of testosterone, but higher than that, the testosterone gets the upper hand.

What is his testosterone level? If it is high then ADT would probably be a good idea along with the Nubeqa. Even better would probably be to use estradiol patches instead. The patch trial Completed in England recently and showed that estradiol worked just the same as ADT, but had many fewer side effects. It easy easier on your cardiovascular system, On your bones (osteoporosis), causes fewer hot flashes and less brain fog. If your doctor has not heard of the patch trial, there is a lot of information about it so come back and we can help you.

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Thanks so much for your response! Interesting response and it makes sense but can't find any documentation that specifies that Nubeqa works with a lower T level but considering it is recommended along with ADT and not by itself for metastatic crcp it makes sense! I believe I have watched the video you have mentioned but completely forgot so thank you again! His MOC has not done a Testosterone test or Estradiol test but his Endocronologist did a test on 8/1/2024 (8.5 monts after being on Enzalumatide and about 3 months after he he started the Nubeqa) and his Test was 472 and Est was 38.1. We were told that the 38.1. Guess we need another set of tests to prove the point to the MOC. I have read about the Estradiol patches but cannot remember what clinical trial(s).