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What are the long-term positive/negatives of taking osteoporosis meds?

Osteoporosis & Bone Health | Last Active: May 2 12:56pm | Replies (22)
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@mayblin

While we wait for a response from @gently, I’d like to share this publication indicating “modeling-based bone formation” by Evenity:
https://pubmed.ncbi.nlm.nih.gov/34633116/
I’m attaching a picture below to show the modeling based bone formation over quiescent surfaces - middle part of the picture. Interesting comparison: remodeling based bone formation over remodeled surfaces (top) as in the case for teriparatide and abaloparatide.

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Replies to "While we wait for a response from @gently, I’d like to share this publication indicating “modeling-based..."
newenglandtransplant | @newenglandtransplant | Apr 24 9:32pm

Thank you, @mayblin This is helpful.

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gently | @gently | Apr 26 1:17am

Mayblin, hi.
That's what I was going to say. Now what am I going to say. Both of your citation choices would have been mine. In the past I've detected that we may have a slight difference of opinion on Evenity.
You've learned that it adds bone, not just in the first 2 or 4 months, but intermittently throughout treatment. Do you weigh in on modeled or remodeled. P1NP rises in the first two months.
love hearing from you

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