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@newenglandtransplant

Hi, @gently I really appreciate the insights you share in this group. They’ve been really helpful to me along the way. It’s apparent that you are quite knowledgeable and seem to closely follow the multitude of data available. I’d love to learn more about the mechanism through which Evenity works, primarily around the building of new bone over old and how this relates to bone quality. I wonder if you could direct me to any studies you find particularly helpful with this, either here or via direct message? I’ve dug around a good bit and am still not quite clear on this. As this is the drug I’m currently taking, I’d like to understand this better. Many thanks for any pointers you are able to provide.

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Replies to "Hi, @gently I really appreciate the insights you share in this group. They’ve been really helpful..."

While we wait for a response from @gently, I’d like to share this publication indicating “modeling-based bone formation” by Evenity:
https://pubmed.ncbi.nlm.nih.gov/34633116/
I’m attaching a picture below to show the modeling based bone formation over quiescent surfaces - middle part of the picture. Interesting comparison: remodeling based bone formation over remodeled surfaces (top) as in the case for teriparatide and abaloparatide.