Can you tell us a bit more? How long have you been taking anastrozole? How severe are the increases? Sounds like this is concerning--have you had a chance to discuss with your oncologist? I'm sure you'll get some useful responses here from other readers.

@jesusmaryjoseph77, I moved your question to this existing discussion:

- Anastrozole...has anyone had an increase in glucose or cholesterol
https://connect.mayoclinic.org/discussion/anastrozole-has-anyone-had-an-increase-in-glucose-or-cholesterol/

If you look up the side effects of Anastrozole, your symptoms are listed. Every drug we are prescribed for B/C has side effects. Some people have minor side effects, and others can have severe side effects.