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Abiraterone Acetate: What were your side effects?

Posted by thomb22 @thomb22, Apr 22 7:12am

Hi, was wondering if anyone is having increased and un bearing side effects from their abiraterone acetate. In my case my insurance company is pushing me to take this medication distributed by Apotex. Excessive sweats and constipation issues. Read whereas this company had numerous violations by the FDA. Price fixing, the biggie is quality control. About the money not patient care. The prescription company I am talking about is humana Medicare.

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jeff Marchi | @jeffmarc | Apr 23 10:47am
In reply to @melcanada "On Abiraterone since Jan PSA still going up to 218 Not happy Oncologist keeps meon it..." + (show)
@melcanada

On Abiraterone since Jan PSA still going up to 218 Not happy Oncologist keeps meon it
Have done Xtandi, Radium 223 and 2 chemo's that caused my lungs to fill with fluid Prednisone and oxygen for 6 moths then Abirat

Is darolutamide better? No insurance issues for me

I did PSMA PET and qualify for LU 177 as C only in bones Had radiation T 4 to T 7 and hip Pain still in shoulder

Advise please

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It’s pretty clear you are castrate resistant, and the drugs are not working for you. At this point, I would think they’d want to do chemo or Pluvicto (lu 177).

Since they have now approved Pluvicto For people who have not had chemo, This may be good for you to try first. Speak to your doctor about that, Find out why one procedure would be better for you than the other.

You may want to have somatic genetic testing to see if any Genetic changes have occurred. They can affect how well Pluvicto works. If you have no genetic issues in your hereditary test, you could still have somatic issues come up in your cancer cells.

Pluvicto genetic issues
RB1, PTen, TP53 are Pluvicto resistant
ATM & BRCA work better with Pluvicto

Since you’ve already had Enzalutamide it is unlikely Darolutamide will work any better . Ask your doctor about this.

REPLY
1 reply
jeff Marchi | @jeffmarc | Apr 23 10:52am
In reply to @thomb22 "Thanks so much for the info. Sorry, I didn't fully explain my situation. I have been..." + (show)
@thomb22

Thanks so much for the info. Sorry, I didn't fully explain my situation. I have been on abiraterone for 5 1/2 years. In the beginning the side effects were bad, with time much better. The point I was trying to make that abiraterone is made by a number of manufacturers and like any medicine, depending on the Indvidual the side effects will vary. When I changed from private insurance to Medicare my insurance company now is dictating what medicine(manufacture) in this case apotex. I have tried before, and the side effects were thru the roof. When I asked for the medicine, I was taking before, they told me they can't regardless of if you can tolerate or not. Company policy not patient care.

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I am a little puzzled about your reaction to different brands of the same drug. I had three different abiraterone brands In the 2 1/2 years, I took it. Didn’t notice any difference at all between them. My side effects were always the same.

Is it possible there was something besides Abbie that was causing the problem?

REPLY
1 reply
melcanada | @melcanada | Apr 23 11:54am
In reply to @jeffmarc "It’s pretty clear you are castrate resistant, and the drugs are not working for you. At..." + (show)
@jeffmarc

It’s pretty clear you are castrate resistant, and the drugs are not working for you. At this point, I would think they’d want to do chemo or Pluvicto (lu 177).

Since they have now approved Pluvicto For people who have not had chemo, This may be good for you to try first. Speak to your doctor about that, Find out why one procedure would be better for you than the other.

You may want to have somatic genetic testing to see if any Genetic changes have occurred. They can affect how well Pluvicto works. If you have no genetic issues in your hereditary test, you could still have somatic issues come up in your cancer cells.

Pluvicto genetic issues
RB1, PTen, TP53 are Pluvicto resistant
ATM & BRCA work better with Pluvicto

Since you’ve already had Enzalutamide it is unlikely Darolutamide will work any better . Ask your doctor about this.

Jump to this post

My PSMA PET Scan approved me for LU 177 Oncologist waiting to see blood results PSA Monday

Abiraterone not working in my view Radiated T 4 to T 10 and hip at leg joint Pain meds now as shoulder still painful

I did genetic test and no family history
Concern over LU 177 affects and OS as they say 15 months once you start it

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dailyeffort | @dailyeffort | Apr 23 12:42pm
In reply to @thomb22 "Thanks." + (show)
@thomb22

Thanks.

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If you want to compare a different brand of abiraterone, see if you can find one at a different pharmacy that works with one of the discount coupon programs like GoodRx that provides a very good cash price and doesn't involve your insurance company.
Bill

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1 reply
thomb22 | @thomb22 | Apr 24 7:20am
In reply to @jeffmarc "I am a little puzzled about your reaction to different brands of the same drug. I..." + (show)
@jeffmarc

I am a little puzzled about your reaction to different brands of the same drug. I had three different abiraterone brands In the 2 1/2 years, I took it. Didn’t notice any difference at all between them. My side effects were always the same.

Is it possible there was something besides Abbie that was causing the problem?

Jump to this post

Thanks for your response. It's a Indvidual issue. Certain people will react differently. The time I switched to apotex the side effects were unbearable. Nothing else changed. The other major point I was making, and I see people didn't catch on was when this does happen, your insurance provider should work with you.

REPLY
larrybas | @larrybas | Apr 25 9:49am
In reply to @dailyeffort "If you want to compare a different brand of abiraterone, see if you can find one..." + (show)
@dailyeffort

If you want to compare a different brand of abiraterone, see if you can find one at a different pharmacy that works with one of the discount coupon programs like GoodRx that provides a very good cash price and doesn't involve your insurance company.
Bill

Jump to this post

I use Mark Cuban’s Cost Plus for Abiraterone Acetate. Costs me $78/month for a month’s supply of 1000 mg daily. Delivered by mail, with tax, comes to around $85. Doesn’t go through insurance. Been using it for one year so far. One more year to go.

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