Hello/ my dr. did put me on 20 mg but after horrible side affects began almost immediately, I told him it was something I was no longer willing to take. I referenced the studies I had read regarding lower doses, my particular tumour and emphasized quality of life was my biggest concern at 71. He ultimately said it was my decision. I am not with the Mayo clinic. A lot of research and thought went into my decision but I feel it was the right decision for me.