I actually have somewhat of a predictable pattern with my bowel movements, where I get into trouble is in the afternoon and know it is best if I can be home then. I know, I wish the doctors would further explain how someone who has primarily diarrhea can have a moderate to large stool burden. They usually just tell me to do a home Miralax clean out. Oh, by the way, I take my Miralax dose all at once in the morning, I am currently on 4 capful daily. I tolerate it fine taking it all at once, but I know everyone is different.