I'm on Gemcitabine + Abraxane + Cisplatin. I just found the email I received from my onco-pharmacist 2 years ago:

For interactions between the extensive supplement list and your chemotherapy, B vitamin components (includes pyroxidine (B6), thiamin (B1), riboflavin (B2), folate (B9), niacin (B3), pantothenic acid (B5)and biotin (B7) are OK. In general, any vitamins or minerals listed a 100% or less of daily recommended requirements are OK.

Avoid any component listed as an antioxidant - this has the potential of reducing the efficacy of cisplatin. These include high levels of Vitamin E, Vitamin C, coenzyme Q, tumeric, and many others. In addition many of these components can add to any bleeding risk, and should be held if your platelets are low (good possibility for any one on gemcitabine, cisplatin and Abraxane).

An additional concern is interaction with enzymes that break down chemotherapy. This does not apply to cisplatin or gemcitabine, but does affect Abraxane. Abraxane is broken down and eliminated from the body with the activity of enzymes 2C8 and 3A4. Quercitin for example inhibits the activity of both these enzymes and could lead to a buildup of the drug (and higher side effects) in your body.

I would recommend holding supplement containing any of these components at levels greater than 100% while receiving gemcitabine, cisplatin, Abraxane.