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Chemo, Lupron & Nubeqa (Triple treatment) Outcomes

Prostate Cancer | Last Active: May 4 6:30pm | Replies (18)

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@rwski79

Colleen - My situation was similar, but occurred over a short period of time. I had a Gleason 9 (4+5) after prostatectomy in July 2024 with rising PSA after surgery, 3 small lung nodules appeared with PSMA and after Eligard injection nodules disappeared by December 2024 and PSA was undetectable. Nubeqa was added to Eligard and one oncologist offered/encouraged adding Chemo (Docetaxel) but I declined for now, as no other metastasis was found and I feared neuropathy complications, as I already have that in my feet. Another reason I declined the "Triple" is that I was told, with or without chemo I would still remain on hormone therapy, Eligard plus Nubeqa or another combination, for the rest of my life. In my opinion and from what I have experienced, side effects of hormone therapy alone are daunting, over time, not to mention the effects of chemo. Another oncologist recommended if the hormone therapy alone is working to keep PSA undetectable and future scans show no metastasis, keep the "Triple" at bay until warranted. I realize the cancer will re-occur, regardless, but less likely with Triple. Quality of life vs. a few more months of life need to be weighed as well - again in my opinion. Other thoughts?

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Replies to "Colleen - My situation was similar, but occurred over a short period of time. I had..."

@rwski79, I noticed that you addressed your question to me. These are great questions to discuss with your team and fellow prostate cancer travellers. I'm not qualified to answer.