Connect
← Return to Gleason 9 SO wants me to stop ADT @6 Mos for look see
Discussion
Gleason 9 SO wants me to stop ADT @6 Mos for look see
Prostate Cancer | Last Active: Apr 21 9:13pm | Replies (27)Comment receiving replies
I'm not saying get off prematurely but eventually you need to take a holiday to determine what you next steps will be. Eventually the ADT will quit working mean while all the time your on it the cancer has simply slowed down not died. At some point you need to determine if it's gone or where it's moving to.
Replies to "I'm not saying get off prematurely but eventually you need to take a holiday to determine..."
True, but the second-generation ARSIs (the "-lutamides") can massively extend the period of time that ADT keeps working for many patients, so a lot of the old common knowledge is out the window now. They're expensive, though, so it might mean an insurance fight in the U.S. for non-metastatic high-risk PCa. 😕
Connect
Well of course you want to stop it at some point - it’s not even good to stay on it for too long; but WHAT is the point at which you stop?
I’m only going from my own experience, Gleason 4+3 unfavorable and recurrence 5 yrs after surgery. I was prescribed 6 months of ADT - which was plenty, believe me…
But for a Gleason 9 (with cribriform?) which came back after 2.5 yrs, you are dealing with a more aggressive cancer. I’ll go one step even further. I would ask a medical oncologist if there is an additional drug I should be on to really wipe this out now.
I agree that the only way to know definitively is to go off ADT and see what happens, but what’s the next step if it starts going up? Chemo? Triplet Therapy?
Honestly, I am not happy thinking about this sh** coming back again for a third time.
Phil