which bisphosphonate after Tymlos with the least side effects?

Posted by 2024tymloshelp @2024tymloshelp, Apr 16 9:50am

Hello- I have moderate osteoporosis and I will be finishing a year of Tymlos soon and will have a new DEXA scan in the fall.
I will need to take a new drug afterwards to save the bone that was created while on Tymlos.
Note: I was already on HRT for 5 years prior to Tymlos.
I am 65 years old.
Every bisphosphonate that I have read about sounds awful to me with their side effects . Hair loss, cancer, broken femurs, teeth problems, jaw problems, and more. So scary! PLEASE tell me- which is the post Tymlos option with the LEAST SERIOUS side effects! thanks

Interested in more discussions like this? Go to the Bones, Joints & Muscles Support Group.

Cancer??? I have never heard that they cause cancer. Where did you read that for the bio phosphates?

REPLY

2024tymloshelp, risedronate brand name Actonel. Do you have a long term plan? Mine is to always return to the anabolic. Except that now I may be able to stay on Forteo. You may have the option of a third year of Tymlos. What has your experience on Tymlos been like.
Some women are using raloxifene or hrt to retain the gains from anabolic bone drugs with success.
You may not have any negative side effects from bisphosphonates, but, like you, I'm avoiding them. In desperation, only, I would take risedronate.
I haven't heard of this class of drug causing cancer. Zoledronic acid the same drug as Reclast is given to prevent metastatic bone cancer at lower doses and more frequent infusions than Reclast.

REPLY

I have taken Actonel (sp?) for 3 years, have had no side effects and just had my Dexa results….my lumbar spine went from -2.6 to -2.0 so I am happy with the result . My doc says I can take a holiday from it in the summer since i had such a good result. I tried just exercise alone a few years ago and that didn’t help at all. It just got worse. I now do the same exercise program plus the drug. Worked for me.

REPLY

Hi, do you have a specific exercise routine you do, and would you share it? Thank you.

REPLY
@curious10

I have taken Actonel (sp?) for 3 years, have had no side effects and just had my Dexa results….my lumbar spine went from -2.6 to -2.0 so I am happy with the result . My doc says I can take a holiday from it in the summer since i had such a good result. I tried just exercise alone a few years ago and that didn’t help at all. It just got worse. I now do the same exercise program plus the drug. Worked for me.

Jump to this post

Thank you so much for this info about Actonel. That option sounds more appealing to me than the others.

I know I have to take something after Tymlos is over - I'm just trying to find an option with the least undesirable side effects!

REPLY
@missey

Cancer??? I have never heard that they cause cancer. Where did you read that for the bio phosphates?

Jump to this post

Sorry - I should've been more specific- I had read only about esophageal cancer as a possible side effect from one of the bisphosphonates

REPLY
@curious10

I have taken Actonel (sp?) for 3 years, have had no side effects and just had my Dexa results….my lumbar spine went from -2.6 to -2.0 so I am happy with the result . My doc says I can take a holiday from it in the summer since i had such a good result. I tried just exercise alone a few years ago and that didn’t help at all. It just got worse. I now do the same exercise program plus the drug. Worked for me.

Jump to this post

I am reasonably faith ful to doing 30 mins of aerobic, usually stair climbing machine for 20 and 10 of the treadmill at 3.7 intensity. Then I do about 6 or 7 machines, always trained at the back ….so the low and high row, the one where you lean up, the one where you pull weights towards you, the abdominal machine, and one free weight. The free weight one is using a 30 lb (started with 10) and kettle bell. I put it on the floor and lift it up to a standing position with knees facilitating the lift. My physiotherapist said to not do chest machines to build up my chest as this will pull me forward and I have scoliosis . So I do anything that says it helps the back. Also do some legs and arms just not to become a fragile old lady Have to say though I DID this routine for two years without the drugs and i got slightly worse. I was pleasantly surprised that the Actonel worked! However i think the exercise is so important not to become weak. I thought i would have to go on Prolia or something other shots but I can go without for a few years. Then I will go back on the Actonel if that is an option. I have two friends who have decided not to go on the drugs because of the potential side effects and I get that , it is scary. I have to share that three of my acquaintances ( not these two) got back compression fractures and I was so scared of that . I play croquet and it would break my heart to stop that. One had to have surgery and has rods in his back. He is reallly infirm looking now , I don’t know if the surgery was successful or not but he has a bump in his back. The other friend is super wholistic person, and when she got the drugs she was researching like crazy until her doc told her “You have no choice about this if you don’t want to end up in a wheelchair” so she is on shots of some kind. I am worrried about the friends who have chosen not to go on the drugs based on the other two friends who have had tough outcomes. I didn’t want to do the Actonel either but I want to continue to do the things I love. Croquet involves bending which strains the back. I need mine to work. The third friend who got compression fractures had to stop playing croquet, at least temporarily. she didn’t know she had osteoporosis and was waiting to see an endocrinologist to see what her options are. she has scoliosis (mild like me) and was told with the compression fractures and the scoliosis that she has an “unstable back” which didn’t sound like a good situation. Re reading this I see i have 5 friends with osteopenia/porosis . Three of them didn’t know about it, and got compression fractures. Of the 3 with compression fractures, one had surgery (the man, just bent down to pick something up and was in incredible pain) , one who is taking shot type drugs, and one who is waiting to see the doc. The other two friends think that doing exercise is enough and one has even decided never to have DEXA Scans . I was convinced the exercise would do the trick too, until it didn’t. Both of these women are beautiful and I know the jaw scenario is so scary. So it is really a scales of the likelihood of that necrosis happening (very small) and the likelihood of a compression fracture. I guess I thought based on the 3 friends with fractures and none with jaw necrosis I am going to go the drug route.

REPLY
@willow5

Hi, do you have a specific exercise routine you do, and would you share it? Thank you.

Jump to this post

I forgot to put that i do the routine i mentioned about five times a week. Also I am a religious sauna user, I don’t know if it helps the bones (but it increases blood flow everywhere so it might) but I do 5 times a week a week for 20 mins at 160 to 180 F. YES it is hot but this is the temp needed for health based on the Finnish Men’s sauna study which you can google. I started out with 5 mins and built up. The study shows Impressive cognitive and heart benefits.

REPLY
@curious10

I forgot to put that i do the routine i mentioned about five times a week. Also I am a religious sauna user, I don’t know if it helps the bones (but it increases blood flow everywhere so it might) but I do 5 times a week a week for 20 mins at 160 to 180 F. YES it is hot but this is the temp needed for health based on the Finnish Men’s sauna study which you can google. I started out with 5 mins and built up. The study shows Impressive cognitive and heart benefits.

Jump to this post

I’m so impressed with five times a week! I do weights 2 times a week and have just started pilates once a week. Only a couple times a week aerobics with my pelaton. I would like to motivate myself to do more aerobic. Hearing what others do is helpful and motivating. Whether it helps my bones or not (which I know it does) i also don’t want to become a weak older person. Going to get hyaluronic injections on my ankle (osteochondral lesion) and hoping that will let me increase my walking. Thanks for sharing!

The sauna is interesting. There is one at my gym. Something to think about

REPLY

I took fosomax for 3 months. Horrible side effects on esophagus and stomach. Reclast sounds like a nightmare. I am looking into red light therapy and more exercise. I actually have a Dr. that said she would never use the osteoporosis drugs.

REPLY
Please sign in or register to post a reply.