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Any long-term success stories from those NOT taking hormone therapy?

Breast Cancer | Last Active: 13 hours ago | Replies (33)
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@myoga

I read something like that a while ago and was surprised that the percentage of resistance is so high! I’m currently taking letrozole after 2 years of anastrozole and exemestane. My er is in the 90%, so I have to take AI hoping that will buy me more time. I also read that taking drug vacation is a good thing specifically with letrozole.
https://pmc.ncbi.nlm.nih.gov/articles/PMC2491346/
We do what we can and hope that it works.

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Replies to "I read something like that a while ago and was surprised that the percentage of resistance..."
thora902 | @thora902 | 4 days ago

I read that too about the resistance, in my case the article said 30-40% develop resistance to AIs. I actually thought of taking a drug vacation myself and asked my oncologist, and of course, they poo pooed it. I am glad to see the article saying it is beneficial. I am going to take 3 weeks off when I go on vacation. Thanks for sharing the article, it confirms my theory.

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